Detalhe da pesquisa
1.
In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy.
Antimicrob Agents Chemother
; 68(3): e0122223, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38265216
2.
Synthesis and evaluation of phenylimidazole FabK inhibitors as new Anti-C. Difficile agents.
Bioorg Med Chem
; 88-89: 117330, 2023 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37224699
3.
A Late-Stage Functionalization Approach to Derivatives of the Pyrano[3,2- a]carbazole Natural Products.
J Org Chem
; 84(9): 5965-5973, 2019 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30969773
4.
Metal-Free Synthesis of 4-Chloroisocoumarins by TMSCl-Catalyzed NCS-Induced Chlorinative Annulation of 2-Alkynylaryloate Esters.
J Org Chem
; 84(24): 16222-16236, 2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31742402
5.
A Copper-Mediated Conjugate Addition Approach to Analogues of Aconitine-Type Diterpenoid Alkaloids.
J Org Chem
; 83(20): 12911-12920, 2018 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30216070
6.
Correction to "Metal-Free Synthesis of 4-Chloroisocoumarins by TMSCl-Catalyzed NCS-Induced Chlorinative Annulation of 2-Alkynylaryloate Esters".
J Org Chem
; 85(21): 14271-14272, 2020 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33112601
7.
A new synthetic approach to 6-unsubstituted phenanthridine and phenanthridine-like compounds under mild and metal-free conditions.
Org Biomol Chem
; 12(28): 5077-81, 2014 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24914621
8.
Evaluation of Fusobacterium nucleatum Enoyl-ACP Reductase (FabK) as a Narrow-Spectrum Drug Target.
ACS Infect Dis
; 10(5): 1612-1623, 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38597503
9.
In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) Inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy.
bioRxiv
; 2023 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37790427